高观祯，男，博士，副教授。毕业于日本九州大学，获生命机能科学农学博士学位。获得2022年度“国家优秀自费留学生奖学金”，福建省高层次人才(C类人才)。曾参与国家重点研发专项（十三五）、国家“973计划”课题、国家自然科学基金面上项目、省尖兵研发攻关计划、省自然科学基金等省部级以上科研项目十余项。主要研究方向为食品生物活性评价与天然食品来源微纳米颗粒研究，已发表30多篇SCI论文，获得授权专利4项，其中近五年以第一作者或通讯作者于发表十余篇SCI论文。
文章列表（近五年）
1. Wang, H., Song, B., Zhou, J., Gao, G.*, Ding, Y., Meng, X., Ke, L., Ding, W., Zhang, S., Chen, T., Rao, P. Fabrication and Characterization of Curcumin-Loaded Nanoparticles Using Licorice Protein Isolate from Radix Glycyrrhizae. Int. J. Biol. Macromol. 2024, 255, 128235.
2. Guanzhen Gao, Jingru Zhou, Huiqin Wang, Lijing Ke, Jianwu Zhou, Yanan Ding, Wei Ding, Suyun Zhang, Pingfan Rao. Fish oil Nano-emulsion Kills Macrophage: Ferroptosis Triggered by Catalase-catalysed Superoxide Eruption. Food Chemistry. 2023, 408(4),135249.
3. Gao, G., Nakamura, S., Asaba, S., Miyata, Y., Nakayama, H., & Matsui, T. Hesperidin Preferentially Stimulates Transient Receptor Potential Vanilloid 1, Leading to NO Production and Mas Receptor Expression in Human Umbilical Vein Endothelial Cells. J. Agric. Food Chem. 2022, 70(36), 11290–11300.
4. Gao, G., Zhou, J., Zhou, J., Wang, H., Ke, L., Ding, Y., Zhang, S., Ding, W., Rao, P., Li, J. Divalent Cations of Magnesium, Iron and Copper Regulate Oxidative Responses and Inflammatory Cytokines in RAW 264.7 Macrophages. Food Control. 2022, 141, 109212.
4. Wang, H., Huang, J., Ding, Y., Zhou, J., Gao, G.*, Han, H., Zhou, J., Ke, L., Rao, P., Chen, T., Zhang, L. Nanoparticles Isolated From Porcine Bone Soup Ameliorated Dextran Sulfate Sodium-Induced Colitis and Regulated Gut Microbiota in Mice. Front. Nutr. 2022, 9, 821404.
5. Gao, G., Zhou, J., Wang, H., Ding, Y., Zhou, J., Chong, PH., Zhu, L., Ke, L., Wang, X., Rao, P., Wang, Q., Zhang, L. Effects of valerate on intestinal barrier function in cultured Caco-2 epithelial cell monolayers. Mol Biol Rep. 2022, 49, 1817-1825.
7. Gao, G., He, C., Wang, H., Guo, J., Ke, L., Zhou, J., Chong, PH., Rao, P. Polysaccharide Nanoparticles from Isatis indigotica Fort. Root Decoction: Diversity, Cytotoxicity, and Antiviral Activity. Nanomaterials. 2021, 12, 30.
8. Gao, G., Zhou, J., Jin, Y., Wang, H., Ding, Y., Zhou, J., Ke, L., Rao, P., Chong, P.H., Wang, Q., et al. Nanoparticles derived from porcine bone soup attenuate oxidative stress-induced intestinal barrier injury in Caco-2 cell monolayer model. J. Funct. Foods 2021, 83, 104573.
9. Gao, G., Wang, H., Zhou, J., Rao, P., Ke, L., Lin, J.J., Sun Pan, B., Zhang, Y., Wang, Q. Isolation and characterization of bioactive proteoglycan-lipid nanoparticles from freshwater clam (Corbicula fluminea Muller) soup. J. Agric. Food Chem. 2021, 69, 1610–1618.
10. Gao, G., Abe, C., Nectoux, A.M., Huang, S.W., Miyata, Y., Tanaka, K., Tanaka, T., Yamamura, H., Matsui, T. Anti-hypertensive effect of hesperidin and hesperidin-containing fermented Mikan tea in spontaneously hypertensive rats. Food Sci. Technol. Res. 2020.
11. Zhou, J.#, Gao, G.#, Zhang, S., Wang, H., Ke, L., Zhou, J., Rao, P., Wang, Q., Li, J. Influences of calcium and magnesium ions on cellular antioxidant activity (CAA) determination. Food Chem. 2020, 320, 126625.
